1cqe: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1cqe.gif|left|200px]]
+{{Seed}}
+[[Image:1cqe.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1cqe|  PDB=1cqe  |  SCENE=  }}
-'''PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN'''
+===PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN===
-==Overview==
+<!--
-The three-dimensional structure of prostaglandin H2 synthase-1, an integral membrane protein, has been determined at 3.5 A resolution by X-ray crystallography. This bifunctional enzyme comprises three independent folding units: an epidermal growth factor domain, a membrane-binding motif and an enzymatic domain. Two adjacent but spatially distinct active sites were found for its haem-dependent peroxidase and cyclooxygenase activities. The cyclooxygenase active site is created by a long, hydrophobic channel that is the site of non-steroidal anti-inflammatory drug binding. The conformation of the membrane-binding motif strongly suggests that the enzyme integrates into only one leaflet of the lipid bilayer and is thus a monotopic membrane protein.
+The line below this paragraph, {{ABSTRACT_PUBMED_8121489}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 8121489 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_8121489}}
 ==About this Structure==
@@ Line 30: / Line 34: @@
 [[Category: Oxidoreductase]]
 [[Category: Peroxidase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:00:09 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:07:36 2008''