1b77: Difference between revisions

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-[[Image:1b77.gif|left|200px]]
+{{Seed}}
+[[Image:1b77.png|left|200px]]
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 {{STRUCTURE_1b77|  PDB=1b77  |  SCENE=  }}
-'''BUILDING A REPLISOME STRUCTURE FROM INTERACTING PIECES: A SLIDING CLAMP COMPLEXED WITH AN INTERACTION PEPTIDE FROM DNA POLYMERASE'''
+===BUILDING A REPLISOME STRUCTURE FROM INTERACTING PIECES: A SLIDING CLAMP COMPLEXED WITH AN INTERACTION PEPTIDE FROM DNA POLYMERASE===
-==Overview==
+<!--
-We have solved the crystal structures of the bacteriophage RB69 sliding clamp, its complex with a peptide essential for DNA polymerase interactions, and the DNA polymerase complexed with primer-template DNA. The editing complex structure shows a partially melted duplex DNA exiting from the exonuclease domain at an unexpected angle and significant changes in the protein structure. The clamp complex shows the C-terminal 11 residues of polymerase bound in a hydrophobic pocket, and it allows docking of the editing and clamp structures together. The peptide binds to the sliding clamp at a position identical to that of a replication inhibitor peptide bound to PCNA, suggesting that the replication inhibitor protein p21CIP1 functions by competing with eukaryotic polymerases for the same binding pocket on the clamp.
+The line below this paragraph, {{ABSTRACT_PUBMED_10535734}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10535734 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10535734}}
 ==About this Structure==
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 [[Category: Replisome]]
 [[Category: Sliding clamp]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 11:09:32 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:26:08 2008''