1aro: Difference between revisions

Revision as of 17:28, 30 June 2008

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File:1aro.png

Template:STRUCTURE 1aro

T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYMET7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME

Template:ABSTRACT PUBMED 9670025

About this StructureAbout this Structure

1ARO is a Protein complex structure of sequences from Enterobacteria phage t7. Full crystallographic information is available from OCA.

ReferenceReference

Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme., Jeruzalmi D, Steitz TA, EMBO J. 1998 Jul 15;17(14):4101-13. PMID:9670025

Page seeded by OCA on Mon Jun 30 17:28:44 2008

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OCA

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-'''T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME'''
+===T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME===
-==Overview==
+<!--
-The T7 RNA polymerase-T7 lysozyme complex regulates phage gene expression during infection of Escherichia coli. The 2.8 A crystal structure of the complex reveals that lysozyme binds at a site remote from the polymerase active site, suggesting an indirect mechanism of inhibition. Comparison of the T7 RNA polymerase structure with that of the homologous pol I family of DNA polymerases reveals identities in the catalytic site but also differences specific to RNA polymerase function. The structure of T7 RNA polymerase presented here differs significantly from a previously published structure. Sequence similarities between phage RNA polymerases and those from mitochondria and chloroplasts, when interpreted in the context of our revised model of T7 RNA polymerase, suggest a conserved fold.
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+{{ABSTRACT_PUBMED_9670025}}
 ==About this Structure==
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 [[Category: Hydrolase]]
 [[Category: Transcription]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 10:37:32 2008''
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