190d: Difference between revisions

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{{STRUCTURE_190d|  PDB=190d  |  SCENE=  }}  
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'''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)'''
===CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)===




==Overview==
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The crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested.
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{{ABSTRACT_PUBMED_7947764}}


==About this Structure==
==About this Structure==
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[[Category: Quadruple helix]]
[[Category: Quadruple helix]]
[[Category: U-dna]]
[[Category: U-dna]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 09:34:52 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:39:12 2008''

Revision as of 15:39, 30 June 2008

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CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)

Template:ABSTRACT PUBMED 7947764

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764

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