1yfg: Difference between revisions

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[[Image:1yfg.gif|left|200px]]
[[Image:1yfg.png|left|200px]]


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==Overview==
{{ABSTRACT_1915284}}
A significantly improved molecular model of yeast initiator tRNA (ytRNA(iMet) has been prepared that gives insight into the structural basis of eukaryotic initiator tRNA's unique function. This study was made possible by X-ray data collected at synchrotron radiation sources with the newly developed technologies of 'imaging plates' and 'storage phosphors'. These data extend beyond the resolution limit of 4.0 A reported previously to a current limit of 3.0 A and are considerably more accurate. Refinement of the model against the new data (R factor = 21.5%) clearly reveals a novel modification and a set of tertiary interactions involving sequence features characteristic of eukaryotic initiator tRNAs. We hypothesize these to be the structural elements responsible for part of the special function of yeast tRNA(iMET).


==About this Structure==
==About this Structure==
The following page contains interesting information on the relation of 1YFG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb15_1.html Transfer RNA]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YFG OCA].  
The following page contains interesting information on the relation of 1YFG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb15_1.html Transfer RNA]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YFG OCA].  
==Reference==
The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination., Basavappa R, Sigler PB, EMBO J. 1991 Oct;10(10):3105-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1915284 1915284]
[[Category: Transfer RNA]]
[[Category: Transfer RNA]]
[[Category: Basavappa, R.]]
[[Category: Basavappa, R.]]
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[[Category: Amino acid transport]]
[[Category: Amino acid transport]]
[[Category: Transfer ribonucleic acid]]
[[Category: Transfer ribonucleic acid]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 16:15:16 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:07:52 2008''

Revision as of 18:07, 26 June 2008

File:1yfg.png

Template:STRUCTURE 1yfg

YEAST INITIATOR TRNA


Template:ABSTRACT 1915284

About this StructureAbout this Structure

The following page contains interesting information on the relation of 1YFG with [Transfer RNA]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 18:07:52 2008

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