Rop protein: Difference between revisions
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*replacement and insertion of glycine residues in loop | *replacement and insertion of glycine residues in loop | ||
*restored of heptad pattern in loop region) ([[1nkd]]) | *restored of heptad pattern in loop region) ([[1nkd]]) | ||
*a single alanine to proline substitution ([[ | *a single alanine to proline substitution ([[1b6q]]) (Pro31, unlike Ala31, is more confor-mationally constrained, the dihedral angles of Ala31 in the wild type molecule are prohibited to Pro, and leads to a folding pathway for a thermodynamically less stable conformation.) | ||
*re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle([[ | *re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle([[1yo7]]) | ||
*ALA2ILE2-6, repacted the hydrophobic core and a new fold ([[ | *ALA2ILE2-6, repacted the hydrophobic core and a new fold ([[1f4n]]) | ||
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