Sandbox 11: Difference between revisions
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This is the member of the pyrimidine salvage pathway proteins. This phosphorylates uridine and cytidine. We can find the homologues of this protein in many species' genome(see KEGG http://www.genome.ad.jp/dbget-bin/www_bget?enzyme+2.7.1.48). However, this protein give us some questions. For example, many species have this protein homologues but don't have adenosine kinase homologue and inosine kinase homologue. This is the big question about nucleoside salvage pathway. | This is the member of the pyrimidine salvage pathway proteins. This phosphorylates uridine and cytidine. We can find the homologues of this protein in many species' genome(see KEGG[http://www.genome.ad.jp/dbget-bin/www_bget?enzyme+2.7.1.48]). However, this protein give us some questions. For example, many species have this protein homologues but don't have adenosine kinase homologue and inosine kinase homologue. This is the big question about nucleoside salvage pathway. | ||
The structure of this protein is clear up only about human homologue. | The structure of this protein is clear up only about human homologue. | ||
This page show the human homologue's structure with the inhibitor, CTP (Red). | This page show the human homologue's structure with the inhibitor, CTP (Red). | ||
<scene name='Sandbox_11/Stick/1'>Stick model scene</scene> | |||
<scene name='Sandbox_11/Secondary_structure/1'>Secondary structure scene</scene> | |||
<scene name='Sandbox_11/1udw/3'>CTP is closed up scene</scene> | <scene name='Sandbox_11/1udw/3'>CTP is closed up scene</scene> | ||
<scene name='Sandbox_11/2udw/1'>the charge scene</scene> | <scene name='Sandbox_11/2udw/1'>the charge scene</scene> | ||
Revision as of 15:14, 27 May 2008
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This is the member of the pyrimidine salvage pathway proteins. This phosphorylates uridine and cytidine. We can find the homologues of this protein in many species' genome(see KEGG[1]). However, this protein give us some questions. For example, many species have this protein homologues but don't have adenosine kinase homologue and inosine kinase homologue. This is the big question about nucleoside salvage pathway.
The structure of this protein is clear up only about human homologue. This page show the human homologue's structure with the inhibitor, CTP (Red).