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| [[Image:2pd5.jpg|left|200px]] | | [[Image:2pd5.jpg|left|200px]] |
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| {{Structure
| | <!-- |
| |PDB= 2pd5 |SIZE=350|CAPTION= <scene name='initialview01'>2pd5</scene>, resolution 1.6Å
| | The line below this paragraph, containing "STRUCTURE_2pd5", creates the "Structure Box" on the page. |
| |SITE= <scene name='pdbsite=AC1:Nap+Binding+Site+For+Residue+A+500'>AC1</scene> and <scene name='pdbsite=AC2:Zst+Binding+Site+For+Residue+A+600'>AC2</scene>
| | You may change the PDB parameter (which sets the PDB file loaded into the applet) |
| |LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZST:3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE+ACETIC+ACID'>ZST</scene>
| | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), |
| |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span>
| | or leave the SCENE parameter empty for the default display. |
| |GENE= ALR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
| | --> |
| |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00248 Aldo_ket_red]</span>
| | {{STRUCTURE_2pd5| PDB=2pd5 | SCENE= }} |
| |RELATEDENTRY=[[2hvn|2HVN]], [[2pd9|2PD9]], [[2pdb|2PDB]], [[2pdc|2PDC]], [[2pdf|2PDF]], [[2pdg|2PDG]], [[2pdh|2PDH]], [[2pdi|2PDI]], [[2pdj|2PDJ]], [[2pdk|2PDK]], [[2pdl|2PDL]], [[2pdm|2PDM]], [[2pdn|2PDN]], [[2pdp|2PDP]], [[2pdq|2PDQ]], [[2pdu|2PDU]], [[2pdw|2PDW]], [[2pdx|2PDX]], [[2pdy|2PDY]] | |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pd5 OCA], [http://www.ebi.ac.uk/pdbsum/2pd5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pd5 RCSB]</span>
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| }} | |
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| '''Human aldose reductase mutant V47I complexed with zopolrestat''' | | '''Human aldose reductase mutant V47I complexed with zopolrestat''' |
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| [[Category: Klebe, G.]] | | [[Category: Klebe, G.]] |
| [[Category: Steuber, H.]] | | [[Category: Steuber, H.]] |
| [[Category: oxidoreductase]] | | [[Category: Oxidoreductase]] |
| [[Category: tim barrel]] | | [[Category: Tim barrel]] |
| [[Category: v47i mutant]] | | [[Category: V47i mutant]] |
| | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 12:53:29 2008'' |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 2 11:57:25 2008'' | |
