2nui: Difference between revisions

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 [[Image:2nui.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 2nui |SIZE=350|CAPTION= <scene name='initialview01'>2nui</scene>, resolution 1.10&Aring;
+The line below this paragraph, containing "STRUCTURE_2nui", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_2nui|  PDB=2nui  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nui OCA], [http://www.ebi.ac.uk/pdbsum/2nui PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2nui RCSB]</span>
-}}
 '''X-ray Structure of synthetic [D83A]RNase A'''
+==Overview==
+The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.
 ==About this Structure==
-NUI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUI OCA].
+NUI is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUI OCA].
 ==Reference==
-Total synthesis by modern chemical ligation methods &amp; high resolution (1.1Angstrom) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2007 Jul 3;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17610259 17610259]
+Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17610259 17610259]
 [[Category: Pancreatic ribonuclease]]
 [[Category: Single protein]]
@@ Line 25: / Line 25: @@
 [[Category: Kent, S B.H.]]
 [[Category: Tereshko, V A.]]
-[[Category: hydrolase]]
+[[Category: Hydrolase]]
-[[Category: synthetic protein]]
+[[Category: Synthetic protein]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:55:37 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:08:38 2008''