2jhp: Difference between revisions

Revision as of 08:56, 4 May 2008

THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE

OverviewOverview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this StructureAbout this Structure

2JHP is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

ReferenceReference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654 Page seeded by OCA on Sun May 4 08:56:08 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 [[Image:2jhp.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 2jhp |SIZE=350|CAPTION= <scene name='initialview01'>2jhp</scene>, resolution 2.50&Aring;
+The line below this paragraph, containing "STRUCTURE_2jhp", creates the "Structure Box" on the page.
-|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY=
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_2jhp|  PDB=2jhp  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhp OCA], [http://www.ebi.ac.uk/pdbsum/2jhp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jhp RCSB]</span>
-}}
 '''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
@@ Line 23: / Line 20: @@
 ==Reference==
 Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
-[[Category: Bluetongue virus 10 (isolate usa)]]
 [[Category: Single protein]]
 [[Category: Grimes, J M.]]
@@ Line 29: / Line 25: @@
 [[Category: Stuart, D I.]]
 [[Category: Sutton, G.]]
-[[Category: core protein]]
+[[Category: Core protein]]
-[[Category: guanylyltransferase]]
+[[Category: Guanylyltransferase]]
-[[Category: methyltransferase]]
+[[Category: Methyltransferase]]
-[[Category: viral capping enzyme]]
+[[Category: Viral capping enzyme]]
-[[Category: viral protein]]
+[[Category: Viral protein]]
-[[Category: virion protein]]
+[[Category: Virion protein]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 08:56:08 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:21 2008''