2fmn: Difference between revisions

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[[Image:2fmn.gif|left|200px]]
[[Image:2fmn.gif|left|200px]]


{{Structure
<!--
|PDB= 2fmn |SIZE=350|CAPTION= <scene name='initialview01'>2fmn</scene>, resolution 2.05&Aring;
The line below this paragraph, containing "STRUCTURE_2fmn", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=4HF:N-[(5-{2-[(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL]ETHYL}-2-THIENYL)CARBONYL]-L-GLUTAMIC+ACID'>4HF</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase_(NAD(P)H) Methylenetetrahydrofolate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.20 1.5.1.20] </span>
or leave the SCENE parameter empty for the default display.
|GENE= metF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
-->
|DOMAIN=
{{STRUCTURE_2fmn| PDB=2fmn  | SCENE= }}  
|RELATEDENTRY=[[2fmo|2FMO]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fmn OCA], [http://www.ebi.ac.uk/pdbsum/2fmn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fmn RCSB]</span>
}}


'''Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase complex with LY309887'''
'''Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase complex with LY309887'''
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Structural perturbations in the Ala --&gt; Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation., Pejchal R, Campbell E, Guenther BD, Lennon BW, Matthews RG, Ludwig ML, Biochemistry. 2006 Apr 18;45(15):4808-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16605249 16605249]
Structural perturbations in the Ala --&gt; Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation., Pejchal R, Campbell E, Guenther BD, Lennon BW, Matthews RG, Ludwig ML, Biochemistry. 2006 Apr 18;45(15):4808-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16605249 16605249]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methylenetetrahydrofolate reductase (NAD(P)H)]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Campbell, E.]]
[[Category: Campbell, E.]]
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[[Category: Matthews, R G.]]
[[Category: Matthews, R G.]]
[[Category: Pejchal, R.]]
[[Category: Pejchal, R.]]
[[Category: flavin]]
[[Category: Flavin]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: reductase]]
[[Category: Reductase]]
[[Category: tim barrel]]
[[Category: Tim barrel]]
 
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