2eb3: Difference between revisions

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[[Image:2eb3.jpg|left|200px]]
[[Image:2eb3.jpg|left|200px]]


{{Structure
<!--
|PDB= 2eb3 |SIZE=350|CAPTION= <scene name='initialview01'>2eb3</scene>, resolution 2.84&Aring;
The line below this paragraph, containing "STRUCTURE_2eb3", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=AC1:Anp+Binding+Site+For+Residue+A+2001'>AC1</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span>
or leave the SCENE parameter empty for the default display.
|GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_2eb3|  PDB=2eb3 |  SCENE= }}  
|RELATEDENTRY=[[2eb2|2EB2]], [[2zge|2ZGE]], [[2zgf|2ZGF]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eb3 OCA], [http://www.ebi.ac.uk/pdbsum/2eb3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eb3 RCSB]</span>
}}


'''Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP'''
'''Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP'''
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[[Category: Yokoyama, S.]]
[[Category: Yokoyama, S.]]
[[Category: Yoshikawa, S.]]
[[Category: Yoshikawa, S.]]
[[Category: atp-binding]]
[[Category: Atp-binding]]
[[Category: cell cycle]]
[[Category: Cell cycle]]
[[Category: disease mutation]]
[[Category: Disease mutation]]
[[Category: ec 2 7.10 1]]
[[Category: Ec 2 7.10 1]]
[[Category: kinase]]
[[Category: Kinase]]
[[Category: national project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: Nppsfa]]
[[Category: phosphorylation]]
[[Category: Phosphorylation]]
[[Category: receptor]]
[[Category: Receptor]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: Rsgi]]
[[Category: structural genomic]]
[[Category: Structural genomic]]
[[Category: transferase]]
[[Category: Transferase]]
[[Category: transmembrane]]
[[Category: Transmembrane]]
[[Category: tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 02:15:39 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:46:23 2008''

Revision as of 02:15, 4 May 2008

File:2eb3.jpg

Template:STRUCTURE 2eb3

Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP


DiseaseDisease

Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this StructureAbout this Structure

2EB3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA. Page seeded by OCA on Sun May 4 02:15:39 2008

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