1zrt: Difference between revisions

Revision as of 17:59, 3 May 2008

Rhodobacter capsulatus cytochrome bc1 complex with stigmatellin bound

OverviewOverview

Ubihydroquinone: cytochrome (cyt)c oxidoreductase, or cyt bc (1), is a widespread, membrane integral enzyme that plays a crucial role during photosynthesis and respiration. It is one of the major contributors of the electrochemical proton gradient, which is subsequently used for ATP synthesis. The simplest form of the cyt bc (1) is found in bacteria, and it contains only the three ubiquitously conserved catalytic subunits: the Fe-S protein, cyt b and cyt c (1). Here we present a preliminary X-ray structure of Rhodobacter capsulatus cyt bc (1) at 3.8 A and compare it to the available structures of its homologues from mitochondria and chloroplast. Using the bacterial enzyme structure, we highlight the structural similarities and differences that are found among the three catalytic subunits between the members of this family of enzymes. In addition, we discuss the locations of currently known critical mutations, and their implications in terms of the cyt bc (1) catalysis.

About this StructureAbout this Structure

1ZRT is a Protein complex structure of sequences from Rhodobacter capsulatus. Full crystallographic information is available from OCA.

ReferenceReference

X-Ray Structure of Rhodobacter Capsulatus Cytochrome bc (1): Comparison with its Mitochondrial and Chloroplast Counterparts., Berry EA, Huang LS, Saechao LK, Pon NG, Valkova-Valchanova M, Daldal F, Photosynth Res. 2004;81(3):251-75. PMID:16034531 Page seeded by OCA on Sat May 3 17:59:33 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 [[Image:1zrt.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 1zrt |SIZE=350|CAPTION= <scene name='initialview01'>1zrt</scene>, resolution 3.50&Aring;
+The line below this paragraph, containing "STRUCTURE_1zrt", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span>
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1zrt|  PDB=1zrt  |  SCENE=  }}
-|RELATEDENTRY=[[1pp9|1PP9]], [[1kb9|1KB9]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zrt OCA], [http://www.ebi.ac.uk/pdbsum/1zrt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zrt RCSB]</span>
-}}
 '''Rhodobacter capsulatus cytochrome bc1 complex with stigmatellin bound'''
@@ Line 32: / Line 29: @@
 [[Category: Saechao, L K.]]
 [[Category: Valkova-Valchanov, M.]]
-[[Category: complex iii]]
+[[Category: Complex iii]]
-[[Category: cytochrome b]]
+[[Category: Cytochrome b]]
-[[Category: cytochrome bc1]]
+[[Category: Cytochrome bc1]]
-[[Category: cytochrome c1]]
+[[Category: Cytochrome c1]]
-[[Category: heme protein]]
+[[Category: Heme protein]]
-[[Category: membrane protein]]
+[[Category: Membrane protein]]
-[[Category: oxidoreductase]]
+[[Category: Oxidoreductase]]
-[[Category: redox enzyme]]
+[[Category: Redox enzyme]]
-[[Category: respiratory chain]]
+[[Category: Respiratory chain]]
-[[Category: rieske iron sulfur protein]]
+[[Category: Rieske iron sulfur protein]]
-[[Category: stigmatellin]]
+[[Category: Stigmatellin]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 17:59:33 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:40:47 2008''