1xl5: Difference between revisions

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[[Image:1xl5.gif|left|200px]]
[[Image:1xl5.gif|left|200px]]


{{Structure
<!--
|PDB= 1xl5 |SIZE=350|CAPTION= <scene name='initialview01'>1xl5</scene>, resolution 1.73&Aring;
The line below this paragraph, containing "STRUCTURE_1xl5", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=190:N-{(1S)-1-(3-BROMOBENZYL)-4-[(4-BROMOPHENYL)SULFONYL]-6-METHYL-2-OXOHEPTYL}-2-(2,6-DIMETHYLPHENOXY)ACETAMIDE'>190</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
or leave the SCENE parameter empty for the default display.
|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
-->
|DOMAIN=
{{STRUCTURE_1xl5| PDB=1xl5  | SCENE= }}  
|RELATEDENTRY=[[1hvi|1HVI]], [[1ajx|1AJX]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl5 OCA], [http://www.ebi.ac.uk/pdbsum/1xl5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xl5 RCSB]</span>
}}


'''HIV-1 Protease in complex with amidhyroxysulfone'''
'''HIV-1 Protease in complex with amidhyroxysulfone'''
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[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
[[Category: Specker, E.]]
[[Category: Specker, E.]]
[[Category: amidhydroxysulfone inhibitor]]
[[Category: Amidhydroxysulfone inhibitor]]
[[Category: aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: hiv protease]]
[[Category: Hiv protease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 15:10:25 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:51:09 2008''

Revision as of 15:10, 3 May 2008

File:1xl5.gif

Template:STRUCTURE 1xl5

HIV-1 Protease in complex with amidhyroxysulfone


About this StructureAbout this Structure

1XL5 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136 Page seeded by OCA on Sat May 3 15:10:25 2008

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