8xu7: Difference between revisions

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-'''Unreleased structure'''
-The entry 8xu7 is ON HOLD  until Paper Publication
+==Crystal structure of Lsd18 in complex with a product==
+<StructureSection load='8xu7' size='340' side='right'caption='[[8xu7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8xu7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lasalocidi Streptomyces lasalocidi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XU7 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ELY:N~6~,N~6~-DIETHYL-L-LYSINE'>ELY</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=LSB:(4R,5S)-3-[(2R,3S,4S)-2-ETHYL-5-[(3R)-2-ETHYL-3-[2-[(2R,3R)-2-ETHYL-3-METHYL-OXIRAN-2-YL]ETHYL]OXIRAN-2-YL]-3-HYDROXY-4-METHYL-PENTANOYL]-4-METHYL-5-PHENYL-1,3-OXAZOLIDIN-2-ONE'>LSB</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xu7 OCA], [https://pdbe.org/8xu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xu7 RCSB], [https://www.ebi.ac.uk/pdbsum/8xu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xu7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LSD18_STRLS LSD18_STRLS] May catalyze the stereoselective double epoxidation reaction leading to bisepoxyprelasalocid A, a bisepoxide intermediate in the biosynthesis of the polyether antibiotic lasalocid A.<ref>PMID:19025863</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Streptomyces lasalocidi]]
+[[Category: Chen X]]
+[[Category: Deng YM]]