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==Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome missegregation and a rare neurodevelopmental disease== | |||
<StructureSection load='8qsu' size='340' side='right'caption='[[8qsu]], [[Resolution|resolution]] 2.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8qsu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QSU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qsu OCA], [https://pdbe.org/8qsu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qsu RCSB], [https://www.ebi.ac.uk/pdbsum/8qsu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qsu ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CI114_HUMAN CI114_HUMAN] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Abad MA]] | |||
[[Category: Jeyaprakash AA]] | |||
Latest revision as of 10:08, 23 October 2024
Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome missegregation and a rare neurodevelopmental diseaseBi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome missegregation and a rare neurodevelopmental disease
Structural highlights
Function |
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