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==Crystal structure of orphan G protein-coupled receptor 6, pseudoapo form== | |||
<StructureSection load='8tf5' size='340' side='right'caption='[[8tf5]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8tf5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TF5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=P15:2,5,8,11,14,17-HEXAOXANONADECAN-19-OL'>P15</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tf5 OCA], [https://pdbe.org/8tf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tf5 RCSB], [https://www.ebi.ac.uk/pdbsum/8tf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tf5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/GPR6_HUMAN GPR6_HUMAN] Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Barekatain M]] | |||
[[Category: Beresford M]] | |||
[[Category: Bliesath J]] | |||
[[Category: Brice N]] | |||
[[Category: Carlson L]] | |||
[[Category: Cherezov V]] | |||
[[Category: Han GW]] | |||
[[Category: Hua T]] | |||
[[Category: Johansson L]] | |||
[[Category: Katritch V]] | |||
[[Category: Lam JH]] | |||
[[Category: Liu Z]] | |||
[[Category: Lutomski C]] | |||
[[Category: Monenschein H]] | |||
[[Category: Murphy S]] | |||
[[Category: Popov P]] | |||
[[Category: Robinson CV]] | |||
[[Category: Russo J]] | |||
[[Category: Sadybekov AV]] | |||
[[Category: Saikatendu KS]] | |||
[[Category: Schiffer HH]] | |||
[[Category: Sun H]] | |||
Latest revision as of 09:15, 4 December 2024
Crystal structure of orphan G protein-coupled receptor 6, pseudoapo formCrystal structure of orphan G protein-coupled receptor 6, pseudoapo form
Structural highlights
FunctionC562_ECOLX Electron-transport protein of unknown function.GPR6_HUMAN Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). |
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