8tf1: Difference between revisions

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-'''Unreleased structure'''
-The entry 8tf1 is ON HOLD  until Paper Publication
+==Crystal Structure of Pyridoxal Reductase (PDXI)in complex with NADPH and Pyridoxal==
+<StructureSection load='8tf1' size='340' side='right'caption='[[8tf1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Donkor, A.K., Safo, M.K., Musayev, F.N.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8tf1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TF1 FirstGlance]. <br>
-Description: Crystal Structure of Pyridoxal Reductase (PDXI)in complex with NADPH and Pyridoxal
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=UEG:4,5-BIS(HYDROXYMETHYL)-2-METHYL-PYRIDIN-3-OL'>UEG</scene></td></tr>
-[[Category: Safo, M.K]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tf1 OCA], [https://pdbe.org/8tf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tf1 RCSB], [https://www.ebi.ac.uk/pdbsum/8tf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tf1 ProSAT]</span></td></tr>
-[[Category: Musayev, F.N]]
+</table>
-[[Category: Donkor, A.K]]
+== Function ==
+[https://www.uniprot.org/uniprot/PDXI_ECOLI PDXI_ECOLI] Catalyzes the NAD(P)H-dependent reduction of pyridoxal to pyridoxine in vitro. Is not able to reduce 4-pyridoxate, and to oxidize pyridoxine or pyridoxamine (PubMed:27941785). Has Kemp eliminase activity towards the non-physiological substrate 5-nitrobenzisoxazole, producing 4-nitro-2-cyanophenol; this activity is not considered to be physiologically relevant (PubMed:21332126).<ref>PMID:21332126</ref> <ref>PMID:27941785</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli]]
+[[Category: Large Structures]]
+[[Category: Donkor AK]]
+[[Category: Musayev FN]]
+[[Category: Safo MK]]