8so8: Difference between revisions

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'''Unreleased structure'''


The entry 8so8 is ON HOLD  until Paper Publication
==Crystal structure of an N-terminally truncated variant of Escherichia coli RapA==
 
<StructureSection load='8so8' size='340' side='right'caption='[[8so8]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8so8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SO8 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.607&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8so8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8so8 OCA], [https://pdbe.org/8so8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8so8 RCSB], [https://www.ebi.ac.uk/pdbsum/8so8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8so8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAPA_ECOLI RAPA_ECOLI] Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity).<ref>PMID:11751638</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Ji X]]
[[Category: Kakar S]]
[[Category: Shaw GX]]

Latest revision as of 10:18, 3 July 2024

Crystal structure of an N-terminally truncated variant of Escherichia coli RapACrystal structure of an N-terminally truncated variant of Escherichia coli RapA

Structural highlights

8so8 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.607Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RAPA_ECOLI Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity).[1]

References

  1. ↑ Sukhodolets MV, Cabrera JE, Zhi H, Jin DJ. RapA, a bacterial homolog of SWI2/SNF2, stimulates RNA polymerase recycling in transcription. Genes Dev. 2001 Dec 15;15(24):3330-41. PMID:11751638 doi:http://dx.doi.org/10.1101/gad.936701

8so8, resolution 2.61Å

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