8c21: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8c21 is ON HOLD  until Paper Publication
+==Tetrameric 5-HT3A receptor in Salipro (holo, asymmetric)==
+<StructureSection load='8c21' size='340' side='right'caption='[[8c21]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
-Authors: Introini, B., Kudryashev, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8c21]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C21 FirstGlance]. <br>
-Description: Tetrameric 5-HT3A receptor in Salipro (holo, asymmetric)
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SRO:SEROTONIN'>SRO</scene></td></tr>
-[[Category: Introini, B]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c21 OCA], [https://pdbe.org/8c21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c21 RCSB], [https://www.ebi.ac.uk/pdbsum/8c21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c21 ProSAT]</span></td></tr>
-[[Category: Kudryashev, M]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Introini B]]
+[[Category: Kudryashev M]]