8hck: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hck OCA], [https://pdbe.org/8hck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hck RCSB], [https://www.ebi.ac.uk/pdbsum/8hck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hck ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hck OCA], [https://pdbe.org/8hck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hck RCSB], [https://www.ebi.ac.uk/pdbsum/8hck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hck ProSAT]</span></td></tr>
</table>
</table>
== Function ==
 
[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
==See Also==
== References ==
*[[3D structures of syntenin|3D structures of syntenin]]
<references/>
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</StructureSection>
</StructureSection>

Latest revision as of 12:41, 17 October 2024

NMR fragment-based screening against the two PDZ do-mains of MDA-9NMR fragment-based screening against the two PDZ do-mains of MDA-9

Structural highlights

8hck is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

8hck, resolution 2.00Å

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OCA