FirstGlance/Visualizing Conservation: Difference between revisions
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[[FirstGlance/Index|FirstGlance in Jmol]] is the easiest-to-use tool for visualizing, understanding, and sharing protein molecular structure. It offers guided exploration with extensive explanations and examples, yet provides ample power for advanced users. With a few mouse clicks, any molecular scene can be saved as an '''animation (GIF file) ready to drop into a Powerpoint Slide''' -- see examples below, and [http://tinyurl.com/movingmolecules tinyurl.com/movingmolecules]. | [[FirstGlance/Index|FirstGlance in Jmol]] is the easiest-to-use tool for visualizing, understanding, and sharing protein molecular structure. It offers guided exploration with extensive explanations and examples, yet provides ample power for advanced users. With a few mouse clicks, any molecular scene can be saved as an '''animation (GIF file) ready to drop into a Powerpoint Slide''' -- see examples below, and [http://tinyurl.com/movingmolecules tinyurl.com/movingmolecules]. | ||
Among many conveniences offered by FirstGlance, it is easy to see the levels of [[ConSurf/Index|evolutionary conservation determined by ConSurf]] for '''amino acids of special interest'''. Below is an overview with some illustrated examples. | Among many conveniences offered by FirstGlance, it is easy to see the levels of [[ConSurf/Index|evolutionary conservation determined by ConSurf]] for '''amino acids of special interest'''. Below is an overview with some illustrated examples. Here are [[ConSurf/Index|instructions for running ConSurf]] on proteins of interest. Note that you '''cannot''' use FirstGlance to visualize results from the ConSurf Database, ConSurfDB. Unfortunately, the interface to FirstGlance was removed from ConSurfDB PDB files in 2022. | ||
There are 2 ways to analyzie your own ConSurf results in FirstGlance: | There are 2 ways to analyzie your own ConSurf results in FirstGlance: | ||
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:2. At the ConSurf results page, under the heading ''PDB Files'', right click on ''PDB File with ConSurf Results in its Header, for FirstGlance in Jmol'' and select '''Copy Link Address'''. Then, at FirstGlance, click [http://www.bioinformatics.org/firstglance/fgij/where.htm#u enter a molecule's URL], paste the address into the slot, and click Submit. | :2. At the ConSurf results page, under the heading ''PDB Files'', right click on ''PDB File with ConSurf Results in its Header, for FirstGlance in Jmol'' and select '''Copy Link Address'''. Then, at FirstGlance, click [http://www.bioinformatics.org/firstglance/fgij/where.htm#u enter a molecule's URL], paste the address into the slot, and click Submit. | ||
==Initial View of Conservation== | ==Initial View of Conservation== | ||