7rrd: Difference between revisions

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==IDO1 IN COMPLEX WITH COMPOUND S-1==
==IDO1 IN COMPLEX WITH COMPOUND S-1==
<StructureSection load='7rrd' size='340' side='right'caption='[[7rrd]]' scene=''>
<StructureSection load='7rrd' size='340' side='right'caption='[[7rrd]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRD FirstGlance]. <br>
<table><tr><td colspan='2'>[[7rrd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRD FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrd OCA], [https://pdbe.org/7rrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrd RCSB], [https://www.ebi.ac.uk/pdbsum/7rrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrd ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6IZ:3-[4-(1H-benzimidazol-2-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide'>6IZ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrd OCA], [https://pdbe.org/7rrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrd RCSB], [https://www.ebi.ac.uk/pdbsum/7rrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref>
==See Also==
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lesburg CA]]
[[Category: Lesburg CA]]

Latest revision as of 12:08, 17 October 2024

IDO1 IN COMPLEX WITH COMPOUND S-1IDO1 IN COMPLEX WITH COMPOUND S-1

Structural highlights

7rrd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.76Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

I23O1_HUMAN Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.[1]

See Also

References

  1. Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 2007 Aug 1;67(15):7082-7. PMID:17671174 doi:http://dx.doi.org/10.1158/0008-5472.CAN-07-1872

7rrd, resolution 2.76Å

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