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==== | ==The SRM module of SWI/SNF-nucleosome complex== | ||
<StructureSection load='7egm' size='340' side='right'caption='[[7egm]]' scene=''> | <StructureSection load='7egm' size='340' side='right'caption='[[7egm]], [[Resolution|resolution]] 3.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7egm]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EGM FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7egm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7egm OCA], [https://pdbe.org/7egm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7egm RCSB], [https://www.ebi.ac.uk/pdbsum/7egm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7egm ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7egm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7egm OCA], [https://pdbe.org/7egm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7egm RCSB], [https://www.ebi.ac.uk/pdbsum/7egm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7egm ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SNF2_YEAST SNF2_YEAST] Involved in transcriptional activation. Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Chen KJ]] | |||
[[Category: Chen ZC]] | |||
[[Category: He ZY]] | |||
[[Category: Ye YP]] | |||
Latest revision as of 08:43, 5 June 2024
The SRM module of SWI/SNF-nucleosome complexThe SRM module of SWI/SNF-nucleosome complex
Structural highlights
FunctionSNF2_YEAST Involved in transcriptional activation. Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. See Also |
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