Cathepsin 3D structures: Difference between revisions
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**[[3cbj]], [[3cbk]] – hMCTSB (mutant)+chagasin<br /> | **[[3cbj]], [[3cbk]] – hMCTSB (mutant)+chagasin<br /> | ||
**[[5mbl]], [[5mbm]] – hMCTSB + darpin <br /> | **[[5mbl]], [[5mbm]] – hMCTSB + darpin <br /> | ||
**[[6ay2]] – hMCTSB + inhibitor <br /> | **[[6ay2]], [[8b4t]], [[8he9]], [[8hei]], [[8hen]] – hMCTSB + inhibitor <br /> | ||
**[[8b5f]] – hMCTSB + carbamate inhibitor | |||
**[[2dc6]], [[2dc7]], [[2dc8]], [[2dc9]], [[2dca]], [[2dcb]], [[2dcc]], [[2dcd]] – bMCTSB+inhibitor – bovine<br /> | **[[2dc6]], [[2dc7]], [[2dc8]], [[2dc9]], [[2dca]], [[2dcb]], [[2dcc]], [[2dcd]] – bMCTSB+inhibitor – bovine<br /> | ||
**[[1sp4]], [[1csb]] – bMCTSB+epoxysuccinyl inhibitor<br /> | **[[1sp4]], [[1csb]] – bMCTSB+epoxysuccinyl inhibitor<br /> | ||
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**[[3hhi]] – TbCTSB (mutant) residues 23-340+CA074 <br /> | **[[3hhi]] – TbCTSB (mutant) residues 23-340+CA074 <br /> | ||
**[[3mor]] - TbCTSB residues 23-340<br /> | **[[3mor]] - TbCTSB residues 23-340<br /> | ||
**[[3qsd]], [[3s3q]], [[3s3r]] - | |||
* Cathepsin-B1 mature | |||
**[[3qsd]], [[3s3q]], [[3s3r]] - SmCTSB1 (mutant) residues 87-340+ inhibitor – ''Schistosoma mansoni''<br /> | |||
**[[8c9d]], [[8cc2]], [[8ccu]] - SmCTSB1 + gallinamide inhibitor | |||
**[[6yi7]] - SmCTSB1 + azanitrile inhibitor | |||
* Cathepsin-C mature or [[Dipeptidyl peptidase]]-I | * Cathepsin-C mature or [[Dipeptidyl peptidase]]-I | ||
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**[[1t32]] - hMCTSG +piperidine inhibitor<br /> | **[[1t32]] - hMCTSG +piperidine inhibitor<br /> | ||
**[[6vtm]] – hMCTSG + MAP domain-containing protein<br /> | **[[6vtm]] – hMCTSG + MAP domain-containing protein<br /> | ||
**[[8d4s]], [[8d4v]] – hMCTSG + extracellular adherent protein | |||
**[[8d7i]], [[8d7k]], [[9asx]], [[9atk]] – hMCTSG + extracellular adherent protein + neutrophil elastase<br /> | |||
**[[8g24]], [[8g25]], [[8g26]] – hMCTSG + MAP domain-containing protein + neutrophil elastase<br /> | |||
*Procathepsin-H | *Procathepsin-H | ||
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**[[1snk]] - hMCTSK + norleucine inhibitor<br /> | **[[1snk]] - hMCTSK + norleucine inhibitor<br /> | ||
**[[1nl6]], [[1nlj]] - hMCTSK+ azepanone inhibitor<br /> | **[[1nl6]], [[1nlj]] - hMCTSK+ azepanone inhibitor<br /> | ||
**[[1q6k]] - hMCTSK+carbamate inhibitor<br /> | **[[1q6k]], [[7qbl]] - hMCTSK+carbamate inhibitor<br /> | ||
**[[1au0]] - hMCTSK+ diacylaminoethyl ketone inhibitor<br /> | **[[1au0]] - hMCTSK+ diacylaminoethyl ketone inhibitor<br /> | ||
**[[1au2]] - hMCTSK+ propanone inhibitor<br /> | **[[1au2]] - hMCTSK+ propanone inhibitor<br /> | ||
**[[1atk]] – hMCTSK+guanidine inhibitor<br /> | **[[1atk]] – hMCTSK+guanidine inhibitor<br /> | ||
**[[1vsn]], [[5j94]], [[4x6h]], [[4x6i]], [[6qbs]], [[6hgy]], [[6pxf]], [[6qlx]], [[6qm0]], [[7nxl]], [[7qbm]], [[7qbn]], [[7qbo]] - hMCTSK+ inhibitor<br /> | **[[1vsn]], [[5j94]], [[4x6h]], [[4x6i]], [[6qbs]], [[6hgy]], [[6pxf]], [[6qlx]], [[6qm0]], [[7nxl]], [[7nxm]], [[7qbm]], [[7qbn]], [[7qbo]] - hMCTSK+ inhibitor<br /> | ||
**[[6ash]] – hMCTSK (mutant) + inhibitor<br /> | **[[6ash]] – hMCTSK (mutant) + inhibitor<br /> | ||
**[[2ato]] – hMCTSK+myocrisin<br /> | **[[2ato]] – hMCTSK+myocrisin<br /> | ||
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**[[5t6u]] – mMCTSK<br /> | **[[5t6u]] – mMCTSK<br /> | ||
**[[6bki]] – mMCTSK (mutant) <br /> | **[[6bki]] – mMCTSK (mutant) <br /> | ||
**[[8v58]] - mMCTSK + heparan-sulfate | |||
**[[8v57]] – mMCTSK + cystatin-C<br /> | |||
*Procathepsin-L | *Procathepsin-L | ||
**[[1cjl]], [[1cs8]] - hPCTS-L (mutant)<br /> | **[[1cjl]], [[1cs8]] - hPCTS-L (mutant)<br /> | ||
**[[7w33]], [[8gx2]] – hPCTS-L + inhibitor<br /> | |||
**[[7w34]] – hPCTS-L (mutant) + inhibitor<br /> | |||
**[[3qj3]] - PCTS-L (mutant) – ''Tenebrio molitor''<br /> | **[[3qj3]] - PCTS-L (mutant) – ''Tenebrio molitor''<br /> | ||
* Cathepsin-L mature | * Cathepsin-L mature | ||
**[[7z3t]] – hMCTSL <br /> | |||
**[[4axl]] – hMCTSL catalytic domain<br /> | **[[4axl]] – hMCTSL catalytic domain<br /> | ||
**[[4axm]] – hMCTSL catalytic domain + inhibitor<br /> | **[[4axm]] – hMCTSL catalytic domain + inhibitor<br /> | ||
**[[1mhw]] – hMCTSL +tripeptide<br /> | **[[1mhw]] – hMCTSL +tripeptide<br /> | ||
**[[8uac]] – hMCTSL + inhibitor<br /> | |||
**[[7qkb]], [[7qkc]], [[7qkd]], [[7z58]], [[7zs7]], [[7zvf]], [[7zxa]], [[8a4v]], [[8a4w]], [[8a4x]], [[8a5b]], [[8ahv]], [[8b4f]], [[8c77]], [[8ofa]], [[8oza]], [[8prx]], [[8qkb]] – hMCTSL (mutant) + inhibitor<br /> | |||
**[[1icf]] – hMCTSL +MHC class II fragment<br /> | **[[1icf]] – hMCTSL +MHC class II fragment<br /> | ||
**[[3f75]] – MCTSL +CTSL propeptide – ''Toxoplasma gondii''<br /> | **[[3f75]] – MCTSL +CTSL propeptide – ''Toxoplasma gondii''<br /> | ||
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**[[1fh0]] – hMCTSL2 (mutant) +vinyl sulfone inhibitor<br /> | **[[1fh0]] – hMCTSL2 (mutant) +vinyl sulfone inhibitor<br /> | ||
**[[3kfq]] - hMCTSL2 (mutant)+stefin | **[[3kfq]] - hMCTSL2 (mutant)+stefin | ||
**[[7qgw]] - hMCTSL2 (mutant) + calpeptin<br /> | |||
* Procathepsin-S | * Procathepsin-S | ||
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**[[3n3g]], [[3n4c]] - hMCTSS+ pyrimidine inhibitor<br /> | **[[3n3g]], [[3n4c]] - hMCTSS+ pyrimidine inhibitor<br /> | ||
**[[3ovx]] - hMCTSS+ aldehyde inhibitor<br /> | **[[3ovx]] - hMCTSS+ aldehyde inhibitor<br /> | ||
**[[3ovz]] - hMCTSS+ ketoamide inhibitor<br /> | **[[3ovz]], [[9gj2]] - hMCTSS+ ketoamide inhibitor<br /> | ||
**[[5qc4]] – hMCTSS (mutant)+ thioether acetamide<br /> | **[[5qc4]] – hMCTSS (mutant)+ thioether acetamide<br /> | ||
**[[3iej]], [[5qcf]], [[5qce]], [[5qcd]], [[5qcc]], [[5qcg]], [[5qch]], [[5qci]] - hMCTSS (mutant)+pyrazole inhibitor<br /> | **[[3iej]], [[5qcf]], [[5qce]], [[5qcd]], [[5qcc]], [[5qcg]], [[5qch]], [[5qci]] - hMCTSS (mutant)+pyrazole inhibitor<br /> | ||
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**[[5qbu]], [[5qbw]], [[5qbx]], [[5qbz]], [[5qc0]], [[5qc1]], [[5qc2]], [[5qc3]], [[5qc5]], [[5qc6]], [[5qc7]], [[5qc8]], [[5qc9]], [[5qca]], [[5qcb]] – hMCTSS (mutant) + piperidine inhibitor<br /> | **[[5qbu]], [[5qbw]], [[5qbx]], [[5qbz]], [[5qc0]], [[5qc1]], [[5qc2]], [[5qc3]], [[5qc5]], [[5qc6]], [[5qc7]], [[5qc8]], [[5qc9]], [[5qca]], [[5qcb]] – hMCTSS (mutant) + piperidine inhibitor<br /> | ||
**[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | **[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | ||
**[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]], [[6yyn]], [[6yyo]], [[6yyp]], [[6yyq]], [[6yyr]] – hMCTSS+inhibitor<br /> | **[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]], [[6yyn]], [[6yyo]], [[6yyp]], [[6yyq]], [[6yyr]], [[8rnd]] – hMCTSS+inhibitor<br /> | ||
**[[2fye]], [[2g6d]] – hMCTSS (mutant)+inhibitor<br /> | **[[2fye]], [[2g6d]] – hMCTSS (mutant)+inhibitor<br /> | ||
**[[2fq9]], [[1ms6]] – hMCTSS +nitrile inhibitor<br /> | **[[2fq9]], [[1ms6]] – hMCTSS +nitrile inhibitor<br /> | ||
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**[[4bsq]] - mMCTSS+ morpholine inhibitor<br /> | **[[4bsq]] - mMCTSS+ morpholine inhibitor<br /> | ||
**[[4bpv]], [[4bqv]], [[4bs6]] - mMCTSS +nitrile inhibitor<br /> | **[[4bpv]], [[4bqv]], [[4bs6]] - mMCTSS +nitrile inhibitor<br /> | ||
*Cathepsin-V mature | |||
**[[7q8d]], [[7q8f]], [[7q8g]], [[7q8h]], [[7q8i]], [[7q8j]], [[7q8k]], [[7q8l]], [[7q8m]], [[7q8o]], [[7q8p]], [[7q8q]], [[7q9c]], [[7q9h]], [[7qff]], [[7qfh]], [[7qhj]], [[7qhk]], [[7qns]], [[7qo2]] – hMCTSV (mutant) + peptide | |||
* Procathepsin-X | * Procathepsin-X | ||