6-phosphogluconate dehydrogenase 3D structures: Difference between revisions

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*6PGD
*6PDH 1-483


**[[4gwg]] - h6PGD – human<br />
**[[2pgd]] - s6PGD – sheep<BR />
**[[1pgj]] - 6PGD – ''Trypanosoma brucei''<BR />
**[[2p4q]] - 6PGD – yeast<BR />
**[[2zyg]] - 6PGD (mutant) – ''Klebsiella pneumonia''<BR />
**[[4e21]] - Gm6PGD – ''Geobacter metallireducens''
**[[4gbj]] – Df6PGD – ''Dyadobacter fermentans''<br />
**[[6xeq]] – 6PDH – ''Gluconbacter oxydans''<br />
**[[6vpb]] – 6PDH – ''Gluconacetobacter diazotrophicus''<br />
**[[7cb0]], [[7cb6]] - Sa6PDH – ''Staphylococcus aureus''<br />


*6PGD binary complex
**[[4gwg]] - h6PDH 1-483 – human<br />
**[[2pgd]] - s6PDH – sheep
**[[2p4q]] - 6PDH – yeast
**[[2zyg]] - 6PDH (mutant) – Klebsiella pneumonia
**[[1pgj]] - 6PDH – Trypanosoma brucei


**[[2jkv]] - h6PGD + NADP <BR />
**[[7cb0]], [[7cb6]] - Sa6PDH – Staphylococcus aureus<br />
**[[4gwk]] - h6PGD + 3PG<br />
**[[8i4n]] – 6PDH – Corynebacterium glutamicum<br />
 
*6PDH binary complex
 
**[[2jkv]] - h6PDH + NADP  
**[[4gwk]] - h6PDH + 3PG<br />
**[[5uq9]] - h6PDH + dioxolan derivative<br />
**[[5uq9]] - h6PDH + dioxolan derivative<br />
**[[1pgn]] – s6PGD + Br-NADP<BR />
**[[1pgn]] – s6PDH + Br-NADP  
**[[1pgo]] - s6PGD + NADP<BR />
**[[1pgo]] - s6PDH + NADP
**[[1pgp]] - s6PGD + 6PG<BR />
**[[1pgp]] - s6PDH + 6PG
**[[1pgq]] - s6PGD + AMP<BR />
**[[1pgq]] - s6PDH + AMP
**[[6fqz]] - Pf6PDH + 6PG – ''Plasmodium falciparum''<br />
**[[6fqz]] - Pf6PDH + 6PG – Plasmodium falciparum<br />
**[[6fqy]] - Pf6PDH + NADP <br />
**[[6fqy]] - Pf6PDH + NADP <br />
**[[2zya]] - Ec6PGD (mutant) + 6PG – ''Escherichia coli''<BR />
**[[2zya]] - Ec6PDH (mutant) + 6PG – Escherichia coli
**[[2w8z]], [[2w90]] - 6PGD + 6PG – ''Geobacillus stearothermophilus''<BR />
**[[2zyd]] - Ec6PDH (mutant) + glucose
**[[2iyo]] - Ll6PGD + 6PG – ''Lactococcus lactis''<BR />
**[[2w8z]], [[2w90]] - 6PDH + 6PG – Geobacillus stearothermophilus
**[[2zyd]] - Ec6PGD (mutant) + glucose<br />
**[[2iyo]] - Ll6PDH + 6PG – Lactococcus lactis
**[[3ws7]] – Pc6PGD + NADP – ''Pyrobaculum calidifontis''<br />
**[[6jit]] - Sn6PDH + NADP + quinoline derivative<br />
**[[7cb5]] - Sa6PDH + 6PG <br />
**[[7cb5]] - Sa6PDH + 6PG <br />
**[[7cb2]] - Sa6PDH + NADP <br />
**[[7cb2]] - Sa6PDH + NADP <br />
**[[8c79]] - 6PDH + NADP – Leishmania donovani<br />


*6PGD ternary complex
*6PDH ternary complex


**[[2iz1]] - Ll6PGD + inhibitor + ADP <BR />
**[[2iz1]] - Ll6PDH + inhibitor + ADP  
**[[3fwn]] - Ec6PGD (mutant) + ADP + 6PG<br />
**[[3fwn]] - Ec6PDH (mutant) + ADP + 6PG
**[[3pef]] – Gm6PGD (mutant) + NADP + monophosphoadenosine diphosphoribose<br />
**[[3w6u]] – Pc6PGD + NADP + monophosphoadenosine diphosphoribose <br />
**[[3w6z]] – Pc6PGD (mutant) + NADP + monophosphoadenosine diphosphoribose <br />
**[[5u5g]] - 6PDH + NADP + 2-oxopropyl phosphonate – ''Pseudomonas syringae''<br />
**[[6fqx]] - Pf6PDH + NADP + 6PG <br />
**[[6fqx]] - Pf6PDH + NADP + 6PG <br />


*6PGD quaternary complex
*6PDH quaternary complex
 
**[[2iyp]] - Ll6PDH + ADP + ribulose 5-phosphate + NADP
**[[2iz0]] - Ll6PDH + inhibitor + ADP + NADP
 
*6PDH NAD-binding domain (imine reductase) 1-310
 
**[[7wxe]], [[8kfk]] – IR – Paenibacillus mucilaginosus<br />
**[[9ijb]] – IR – Mycobacterium tuberculosis<br />
**[[4e21]] - GmIR – Geobacter metallireducens
**[[4gbj]] – DfIR – Dyadobacter fermentans<br />
**[[6xeq]] – 6PDH – Gluconbacter oxydans<br />
**[[6vpb]] – 6PDH – Gluconacetobacter diazotrophicus<br />
 
*Imine reductase binary complex
 
**[[6jiz]] - SnIR+ NADP – Stackerbrandita nassauensis <br />
**[[6smt]] - 6PDH + NADP – Mycolicibacterium smegmatis<br />
**[[7osn]] - 6PDH + NADP – Micromonospora<br />
 
*Imine reductase ternary complex
 
**[[3pef]] – GmIR (mutant) + NADP + monophosphoadenosine diphosphoribose<br />
**[[3w6u]] – Pc6PDH + NADP + monophosphoadenosine diphosphoribose – Pyrobaculum calidifontis<br />
**[[3w6z]] – Pc6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose <br />
**[[5u5g]] - 6PDH + NADP + 2-oxopropyl phosphonate – Pseudomonas syringae<br />
**[[6jit]] - Sn6PDH + NADP + quinoline derivative<br />


**[[2iyp]] - Ll6PGD + ADP + ribulose 5-phosphate + NADP<BR />
**[[2iz0]] - Ll6PGD + inhibitor + ADP + NADP<BR />
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Michal Harel