6ql6: Difference between revisions

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<StructureSection load='6ql6' size='340' side='right'caption='[[6ql6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6ql6' size='340' side='right'caption='[[6ql6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ql6]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QL6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QL6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ql6]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QL6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=J8T:[(3~{R})-4-azanyl-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl]+dihydrogen+phosphate'>J8T</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ql6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ql6 OCA], [http://pdbe.org/6ql6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ql6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ql6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ql6 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=J8T:[(3~{R})-4-azanyl-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl]+dihydrogen+phosphate'>J8T</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ql6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ql6 OCA], [https://pdbe.org/6ql6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ql6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ql6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ql6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FAS2_YEAST FAS2_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex.[HAMAP-Rule:MF_00101] [[http://www.uniprot.org/uniprot/FAS1_YEAST FAS1_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
[https://www.uniprot.org/uniprot/FAS2_YEAST FAS2_YEAST] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex.[HAMAP-Rule:MF_00101]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ql6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ql6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Fatty acid synthase 3D structures|Fatty acid synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chari, A]]
[[Category: Chari A]]
[[Category: Graf, B]]
[[Category: Graf B]]
[[Category: Linden, A]]
[[Category: Linden A]]
[[Category: Sautner, V]]
[[Category: Sautner V]]
[[Category: Singh, K]]
[[Category: Singh K]]
[[Category: Stark, H]]
[[Category: Stark H]]
[[Category: Tittmann, K]]
[[Category: Tittmann K]]
[[Category: Urlaub, H]]
[[Category: Urlaub H]]
[[Category: Acetyl transferase]]
[[Category: Acyl carrier protein]]
[[Category: Dehydratase]]
[[Category: Enoyl reductase]]
[[Category: Fatty acid synthase]]
[[Category: Ketoreductase]]
[[Category: Ketosynthase]]
[[Category: Malonyl/palmitoyl transferase]]
[[Category: Phosphopantetheine transferase]]
[[Category: Transferase]]

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