6h3u: Difference between revisions

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==Schmallenberg Virus Glycoprotein Gc Head Domain in Complex with scFv 4B6==
==Schmallenberg Virus Glycoprotein Gc Head Domain in Complex with scFv 4B6==
<StructureSection load='6h3u' size='340' side='right' caption='[[6h3u]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
<StructureSection load='6h3u' size='340' side='right'caption='[[6h3u]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6h3u]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_schmallenberg_virus_(isolate_bovine/bh80/germany/2011) Bovine schmallenberg virus (isolate bovine/bh80/germany/2011)] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H3U FirstGlance]. <br>
<table><tr><td colspan='2'>[[6h3u]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_Schmallenberg_virus_BH80/Germany/2011 Bovine Schmallenberg virus BH80/Germany/2011] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H3U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.168&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1318464 Bovine Schmallenberg virus (isolate Bovine/BH80/Germany/2011)])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3u OCA], [http://pdbe.org/6h3u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h3u RCSB], [http://www.ebi.ac.uk/pdbsum/6h3u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3u OCA], [https://pdbe.org/6h3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h3u RCSB], [https://www.ebi.ac.uk/pdbsum/6h3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GP_SBVBH GP_SBVBH]] Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).  
[https://www.uniprot.org/uniprot/GP_SBVBH GP_SBVBH] Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
<div class="pdbe-citations 6h3u" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6h3u" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Bovine Schmallenberg virus BH80/Germany/2011]]
[[Category: Aebischer, A]]
[[Category: Large Structures]]
[[Category: Beer, M]]
[[Category: Mus musculus]]
[[Category: Brocchi, E]]
[[Category: Aebischer A]]
[[Category: Guardado-Calvo, P]]
[[Category: Beer M]]
[[Category: Haouz, A]]
[[Category: Brocchi E]]
[[Category: Hellert, J]]
[[Category: Guardado-Calvo P]]
[[Category: Reiche, S]]
[[Category: Haouz A]]
[[Category: Rey, F A]]
[[Category: Hellert J]]
[[Category: Wernike, K]]
[[Category: Reiche S]]
[[Category: Envelope glycoprotein]]
[[Category: Rey FA]]
[[Category: Scfv antibody]]
[[Category: Wernike K]]
[[Category: Viral protein]]

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