6fsd: Difference between revisions

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<StructureSection load='6fsd' size='340' side='right'caption='[[6fsd]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6fsd' size='340' side='right'caption='[[6fsd]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fsd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FSD FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fsd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FSD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=E5H:2-(4-phenylphenoxy)-~{N}-(3-piperidin-1-ylpropyl)ethanamide'>E5H</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ache ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=E5H:2-(4-phenylphenoxy)-~{N}-(3-piperidin-1-ylpropyl)ethanamide'>E5H</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fsd OCA], [https://pdbe.org/6fsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fsd RCSB], [https://www.ebi.ac.uk/pdbsum/6fsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fsd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fsd OCA], [http://pdbe.org/6fsd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fsd RCSB], [http://www.ebi.ac.uk/pdbsum/6fsd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fsd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.  
[https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acetylcholinesterase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Ekstrom, F]]
[[Category: Ekstrom F]]
[[Category: Engdahl, C]]
[[Category: Engdahl C]]
[[Category: Forsgren, N]]
[[Category: Forsgren N]]
[[Category: Kamau, L]]
[[Category: Kamau L]]
[[Category: Kindahl, T]]
[[Category: Kindahl T]]
[[Category: Kitur, S]]
[[Category: Kitur S]]
[[Category: Knutsson, S]]
[[Category: Knutsson S]]
[[Category: Kumari, R]]
[[Category: Kumari R]]
[[Category: Lindgren, C]]
[[Category: Lindgren C]]
[[Category: Linusson, A]]
[[Category: Linusson A]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Protein binding]]

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