6aw3: Difference between revisions

No edit summary
No edit summary
 
Line 1: Line 1:


==Crystal structure of the HopQ-CEACAM3 L44Q complex==
==Crystal structure of the HopQ-CEACAM3 L44Q complex==
<StructureSection load='6aw3' size='340' side='right' caption='[[6aw3]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
<StructureSection load='6aw3' size='340' side='right'caption='[[6aw3]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6aw3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6aw3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AW3 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hopQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504]), CEACAM3, CD66D, CGM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw3 OCA], [http://pdbe.org/6aw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw3 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw3 OCA], [https://pdbe.org/6aw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aw3 RCSB], [https://www.ebi.ac.uk/pdbsum/6aw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CEAM3_HUMAN CEAM3_HUMAN]] Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.<ref>PMID:12864848</ref> <ref>PMID:14707113</ref> 
[https://www.uniprot.org/uniprot/H6A3H4_HELPX H6A3H4_HELPX]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43504]]
[[Category: Helicobacter pylori]]
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Bonsor, D A]]
[[Category: Large Structures]]
[[Category: Sundberg, E J]]
[[Category: Bonsor DA]]
[[Category: Cell adhesion]]
[[Category: Sundberg EJ]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA