1tf3: Difference between revisions

Revision as of 09:52, 3 May 2008

TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES

OverviewOverview

The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.

About this StructureAbout this Structure

1TF3 is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.

ReferenceReference

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405 Page seeded by OCA on Sat May 3 09:52:35 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 [[Image:1tf3.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene>
+The line below this paragraph, containing "STRUCTURE_1tf3", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY=
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1tf3|  PDB=1tf3  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [http://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB]</span>
-}}
 '''TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES'''
@@ Line 32: / Line 29: @@
 [[Category: Wuttke, D S.]]
 [[Category: 5s rna gene]]
-[[Category: complex (transcription regulation/dna)]]
+[[Category: Dna]]
-[[Category: dna]]
+[[Category: Dna binding protein]]
-[[Category: dna binding protein]]
+[[Category: Nmr]]
-[[Category: nmr]]
+[[Category: Protein]]
-[[Category: protein]]
+[[Category: Tfiiia]]
-[[Category: tfiiia]]
+[[Category: Transcription factor]]
-[[Category: transcription factor]]
+[[Category: Zinc finger]]
-[[Category: zinc finger]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 09:52:35 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:55:09 2008''