5iec: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5iec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhipicephalus_appendiculatus Rhipicephalus appendiculatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IEC FirstGlance]. <br> | <table><tr><td colspan='2'>[[5iec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhipicephalus_appendiculatus Rhipicephalus appendiculatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IEC FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iec OCA], [https://pdbe.org/5iec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iec RCSB], [https://www.ebi.ac.uk/pdbsum/5iec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iec ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iec OCA], [https://pdbe.org/5iec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iec RCSB], [https://www.ebi.ac.uk/pdbsum/5iec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iec ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/C5I2_RHIMP C5I2_RHIMP] Complement inhibitor (PubMed:27018802). Prevents complement-mediated C5 activation by binding to C5 (PubMed:27018802). Binds C5 at a different binding site than the other tick complement | [https://www.uniprot.org/uniprot/C5I2_RHIMP C5I2_RHIMP] Complement inhibitor (PubMed:27018802). Prevents complement-mediated C5 activation by binding to C5 (PubMed:27018802). Binds C5 at a different binding site than the other tick complement inhibitors OmCI and CirpT1, and the drug eculizumab (By similarity).[UniProtKB:A0A146B485]<ref>PMID:27018802</ref> | ||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||