Platelet-derived growth factors and receptors: Difference between revisions
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Pharmaceutical research has been targeting inhibiting PDGF-PDGFR signaling as a potential for anti-cancer treatments. Strategies of blocking signaling at the cellular level include neutralizing antibiodies for PDGF ligands and receptors, aptamers which are oligonucleic acid or peptide molecules that bind to a specific target molecule, N-terminal processing-deficient PDGFs, and soluble receptors without the kinase domain. | Pharmaceutical research has been targeting inhibiting PDGF-PDGFR signaling as a potential for anti-cancer treatments. Strategies of blocking signaling at the cellular level include neutralizing antibiodies for PDGF ligands and receptors, aptamers which are oligonucleic acid or peptide molecules that bind to a specific target molecule, N-terminal processing-deficient PDGFs, and soluble receptors without the kinase domain. | ||
See also [[PDGFR inhibitors]]. | |||
== Quiz == | == Quiz == | ||