Interleukin-1 receptor-associated kinase: Difference between revisions
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'''Interleukin-1 receptor-associated kinase''' (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins<ref>PMID:8599092</ref>. | '''Interleukin-1 receptor-associated kinase''' (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins<ref>PMID:8599092</ref>. | ||
*'''Interleukin-1 receptor-associated kinase 1''' (IRAK1) is a key link in the chain of events initiated by the binding of ligands to IL-R and Toll-like receptor <ref>PMID:30279971</ref>. | *'''Interleukin-1 receptor-associated kinase 1''' (IRAK1) is a key link in the chain of events initiated by the binding of ligands to IL-R and Toll-like receptor <ref>PMID:30279971</ref>. | ||
*'''Interleukin-1 receptor-associated kinase 2''' (IRAK2) is involved in ER stress-induced cell death<ref>PMID:23724040</ref>. | |||
*'''Interleukin-1 receptor-associated kinase 4''' (IRAK4) has scaffold function in myddosome formation <ref>PMID:30076215</ref>. | *'''Interleukin-1 receptor-associated kinase 4''' (IRAK4) has scaffold function in myddosome formation <ref>PMID:30076215</ref>. | ||