Chemotaxis protein: Difference between revisions

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*'''CheR''' is a SAM-dependent methyltransferase which binds to the C-terminus of some chemotaxis receptors and methylates neighbouring receptor molecules<ref>PMID:9628482</ref>.  See [[Molecular Playground/CheR]] and [[Chemotaxis receptor methyltransferase]].  
*'''CheR''' is a SAM-dependent methyltransferase which binds to the C-terminus of some chemotaxis receptors and methylates neighbouring receptor molecules<ref>PMID:9628482</ref>.  See [[Molecular Playground/CheR]] and [[Chemotaxis receptor methyltransferase]].  
*'''CheA''' is a histidine kinase which donates phosphoric groups to CheB and CheY to control swimming behaviour<ref>PMID:15090507</ref>.  See [[Molecular Playground/CheA]].
*'''CheA''' is a histidine kinase which donates phosphoric groups to CheB and CheY to control swimming behaviour<ref>PMID:15090507</ref>.  See [[Molecular Playground/CheA]].
*'''CheB''' is a methyltransferase catalysing the demethylationof chemotaxis membrane receptors in ''Salmonella typhimurium''<ref>PMID:2991277</ref>.
*[[Molecular Playground/Bacterial Chemotaxis Receptors]] for '''CheW'''<br />
*[[Molecular Playground/Bacterial Chemotaxis Receptors]] for '''CheW'''<br />
*[[Molecular Playground/Bacterial Chemotaxis Complex]] for '''CheA''' and '''CheW'''<br />
*[[Molecular Playground/Bacterial Chemotaxis Complex]] for '''CheA''' and '''CheW'''<br />

Revision as of 11:03, 3 June 2024


Chemotaxis proteins direct cell movement according to certain chemicals in their environment.[1]

3D structures of chemotaxis protein

Chemotaxis protein 3D structures


E. coli CheY (PDB entry 1e6m)

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Adler J, Tso WW. "Decision"-making in bacteria: chemotactic response of Escherichia coli to conflicting stimuli. Science. 1974 Jun 21;184(4143):1292-4. PMID:4598187
  2. Sanna MG, Swanson RV, Bourret RB, Simon MI. Mutations in the chemotactic response regulator, CheY, that confer resistance to the phosphatase activity of CheZ. Mol Microbiol. 1995 Mar;15(6):1069-79. PMID:7623663 doi:10.1111/j.1365-2958.1995.tb02282.x
  3. Djordjevic S, Stock AM. Chemotaxis receptor recognition by protein methyltransferase CheR. Nat Struct Biol. 1998 Jun;5(6):446-50. PMID:9628482
  4. Jahreis K, Morrison TB, Garzón A, Parkinson JS. Chemotactic signaling by an Escherichia coli CheA mutant that lacks the binding domain for phosphoacceptor partners. J Bacteriol. 2004 May;186(9):2664-72. PMID:15090507 doi:10.1128/JB.186.9.2664-2672.2004
  5. Simms SA, Keane MG, Stock J. Multiple forms of the CheB methylesterase in bacterial chemosensing. J Biol Chem. 1985 Aug 25;260(18):10161-8. PMID:2991277

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Michal Harel, Alexander Berchansky, Lynmarie K Thompson, Joel L. Sussman