2uvs: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 ==High Resolution Solid-state NMR structure of Kaliotoxin==
-<StructureSection load='2uvs' size='340' side='right'caption='[[2uvs]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='2uvs' size='340' side='right'caption='[[2uvs]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2uvs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Andmu Andmu]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UVS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2uvs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Androctonus_mauritanicus Androctonus mauritanicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UVS FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ktx|1ktx]], [[2ktx|2ktx]], [[2uvt|2uvt]]</div></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR, 20 models</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uvs OCA], [https://pdbe.org/2uvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uvs RCSB], [https://www.ebi.ac.uk/pdbsum/2uvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uvs ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/KAX31_ANDMA KAX31_ANDMA]] Potent inhibitor of large conductance calcium-activated potassium channels (BK-Ca). Also binds to the dendrotoxin sensitive voltage-dependent potassium channel. It appears to block channel activity by a simple bimolecular inhibition process. Induces a transient period of fast flickering in the channel openings, followed by an almost complete blockade of the channel. Its binding affinity to rat brain synaptosomes is 5-fold higher than this of KTX-3. Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules.
+[https://www.uniprot.org/uniprot/KAX31_ANDMA KAX31_ANDMA] Potent inhibitor of large conductance calcium-activated potassium channels (BK-Ca). Also binds to the dendrotoxin sensitive voltage-dependent potassium channel. It appears to block channel activity by a simple bimolecular inhibition process. Induces a transient period of fast flickering in the channel openings, followed by an almost complete blockade of the channel. Its binding affinity to rat brain synaptosomes is 5-fold higher than this of KTX-3. Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/2uvs_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 24: / Line 24: @@
 __TOC__
 </StructureSection>
-[[Category: Andmu]]
+[[Category: Androctonus mauritanicus]]
 [[Category: Large Structures]]
-[[Category: Baldus, M]]
+[[Category: Baldus M]]
-[[Category: Becker, S]]
+[[Category: Becker S]]
-[[Category: Korukottu, J]]
+[[Category: Korukottu J]]
-[[Category: Lange, A]]
+[[Category: Lange A]]
-[[Category: Pongs, O]]
+[[Category: Pongs O]]
-[[Category: Schneider, R]]
+[[Category: Schneider R]]
-[[Category: Vijayan, V]]
+[[Category: Vijayan V]]
-[[Category: Zweckstetter, M]]
+[[Category: Zweckstetter M]]
-[[Category: Amidation]]
-[[Category: Ionic channel inhibitor]]
-[[Category: Neurotoxin]]
-[[Category: Potassium channel inhibitor]]
-[[Category: Toxin]]