2b68: Difference between revisions
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2b68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Crassostrea_gigas Crassostrea gigas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B68 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2b68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Crassostrea_gigas Crassostrea gigas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B68 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b68 OCA], [https://pdbe.org/2b68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b68 RCSB], [https://www.ebi.ac.uk/pdbsum/2b68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b68 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b68 OCA], [https://pdbe.org/2b68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b68 RCSB], [https://www.ebi.ac.uk/pdbsum/2b68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b68 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ | [https://www.uniprot.org/uniprot/DEFCG_MAGGI DEFCG_MAGGI] Antibacterial peptide mostly active against Gram-positive bacteria (M.lysodeikticus, S.aureus, and the marine bacteria, B.stationis, and M.maritypicum) (PubMed:16246846). It acts by selectively inhibiting peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:20605792). It does not disrupt cell membranes (PubMed:20605792). Is noticeably more potent than Cg-Defh1 (PubMed:20605792). It shows no or limited activities against Gram-negative bacteria and filamentous fungi (PubMed:16246846).<ref>PMID:16246846</ref> <ref>PMID:20605792</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||