2tci: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2tci]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tci 1tci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TCI FirstGlance]. <br> | <table><tr><td colspan='2'>[[2tci]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tci 1tci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TCI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tci OCA], [https://pdbe.org/2tci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tci RCSB], [https://www.ebi.ac.uk/pdbsum/2tci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tci ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tci OCA], [https://pdbe.org/2tci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tci RCSB], [https://www.ebi.ac.uk/pdbsum/2tci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tci ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/INS_PIG INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Dodson | [[Category: Dodson EJ]] | ||
[[Category: Dodson | [[Category: Dodson GG]] | ||
[[Category: Moody | [[Category: Moody PCE]] | ||
[[Category: Whittingham | [[Category: Whittingham JL]] | ||