2qkh: Difference between revisions
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<StructureSection load='2qkh' size='340' side='right'caption='[[2qkh]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2qkh' size='340' side='right'caption='[[2qkh]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2qkh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2qkh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900086:methyl-beta-cyclodextrin'>PRD_900086</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene>, <scene name='pdbligand=ZB0:(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4-dimethoxy-oxane-2,5-diol'>ZB0</scene>, <scene name='pdbligand=ZB1:(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-methoxy-oxane-2,3,5-triol'>ZB1</scene>, <scene name='pdbligand=ZB2:2-O-methyl-alpha-D-glucopyranose'>ZB2</scene>, <scene name='pdbligand=ZB3:(2S,3R,4S,5S,6R)-3-methoxy-6-(methoxymethyl)oxane-2,4,5-triol'>ZB3</scene></td></tr> | ||
< | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkh OCA], [https://pdbe.org/2qkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkh RCSB], [https://www.ebi.ac.uk/pdbsum/2qkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkh OCA], [https://pdbe.org/2qkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkh RCSB], [https://www.ebi.ac.uk/pdbsum/2qkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/GIP_HUMAN GIP_HUMAN] Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkh_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkh_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Demuth | [[Category: Demuth H-U]] | ||
[[Category: Fanghanel | [[Category: Fanghanel J]] | ||
[[Category: Kleinschmidt | [[Category: Kleinschmidt M]] | ||
[[Category: Manhart | [[Category: Manhart S]] | ||
[[Category: Neumann | [[Category: Neumann P]] | ||
[[Category: Parthier | [[Category: Parthier C]] | ||
[[Category: Rahfeld | [[Category: Rahfeld J-U]] | ||
[[Category: Rudolph | [[Category: Rudolph R]] | ||
[[Category: Schlenzig | [[Category: Schlenzig D]] | ||
[[Category: Stubbs | [[Category: Stubbs MT]] | ||