2ova: Difference between revisions
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<StructureSection load='2ova' size='340' side='right'caption='[[2ova]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='2ova' size='340' side='right'caption='[[2ova]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ova]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ova]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OVA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ova FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ova OCA], [https://pdbe.org/2ova PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ova RCSB], [https://www.ebi.ac.uk/pdbsum/2ova PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ova ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ova FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ova OCA], [https://pdbe.org/2ova PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ova RCSB], [https://www.ebi.ac.uk/pdbsum/2ova PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ova ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CO8G_HUMAN CO8G_HUMAN] C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ov/2ova_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ov/2ova_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Brannen | [[Category: Brannen C]] | ||
[[Category: Chiswell | [[Category: Chiswell B]] | ||
[[Category: Lebioda | [[Category: Lebioda L]] | ||
[[Category: Lovelace | [[Category: Lovelace LL]] | ||
[[Category: Ortlund | [[Category: Ortlund EA]] | ||
[[Category: Sodetz | [[Category: Sodetz JM]] | ||