7rjr: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rjr OCA], [https://pdbe.org/7rjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rjr RCSB], [https://www.ebi.ac.uk/pdbsum/7rjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rjr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rjr OCA], [https://pdbe.org/7rjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rjr RCSB], [https://www.ebi.ac.uk/pdbsum/7rjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rjr ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
== Function ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).


==See Also==
==See Also==
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 12:34, 9 October 2024

Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with BCLTF1Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with BCLTF1

Structural highlights

7rjr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.45Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

7rjr, resolution 1.45Å

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OCA