6h38: Difference between revisions

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==The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide.==
==The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide.==
<StructureSection load='6h38' size='340' side='right' caption='[[6h38]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='6h38' size='340' side='right'caption='[[6h38]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6h38]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H38 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6h38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H38 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FKK:4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide'>FKK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6h2z|6h2z]], [[6h33|6h33]], [[6h34|6h34]], [[6h36|6h36]], [[6h37|6h37]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FKK:4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide'>FKK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h38 OCA], [https://pdbe.org/6h38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h38 RCSB], [https://www.ebi.ac.uk/pdbsum/6h38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h38 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h38 OCA], [http://pdbe.org/6h38 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h38 RCSB], [http://www.ebi.ac.uk/pdbsum/6h38 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h38 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CAH7_HUMAN CAH7_HUMAN]] Reversible hydration of carbon dioxide.  
[https://www.uniprot.org/uniprot/CAH7_HUMAN CAH7_HUMAN] Reversible hydration of carbon dioxide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6h38" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6h38" style="background-color:#fffaf0;"></div>
==See Also==
*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Angeli, A]]
[[Category: Large Structures]]
[[Category: Buemi, M R]]
[[Category: Angeli A]]
[[Category: Buonanno, M]]
[[Category: Buemi MR]]
[[Category: Ferro, S]]
[[Category: Buonanno M]]
[[Category: Fiore, A Di]]
[[Category: De Luca L]]
[[Category: Gitto, R]]
[[Category: De Sarro G]]
[[Category: Luca, L De]]
[[Category: De Simone G]]
[[Category: Mancuso, F]]
[[Category: Di Fiore A]]
[[Category: Monti, S M]]
[[Category: Ferro S]]
[[Category: Russo, E]]
[[Category: Gitto R]]
[[Category: Sarro, G De]]
[[Category: Mancuso F]]
[[Category: Simone, G De]]
[[Category: Monti SM]]
[[Category: Supuran, C T]]
[[Category: Russo E]]
[[Category: Lyase]]
[[Category: Supuran CT]]
[[Category: Protein-inhibitor binding]]

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