3bru: Difference between revisions

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<StructureSection load='3bru' size='340' side='right'caption='[[3bru]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3bru' size='340' side='right'caption='[[3bru]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bru]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhos4 Rhos4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bru]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides_2.4.1 Cereibacter sphaeroides 2.4.1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRU FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RSP_1435, RHOS4_00080 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272943 RHOS4])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bru OCA], [https://pdbe.org/3bru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bru RCSB], [https://www.ebi.ac.uk/pdbsum/3bru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bru ProSAT], [https://www.topsan.org/Proteins/MCSG/3bru TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bru OCA], [https://pdbe.org/3bru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bru RCSB], [https://www.ebi.ac.uk/pdbsum/3bru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bru ProSAT], [https://www.topsan.org/Proteins/MCSG/3bru TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ACUR_RHOS4 ACUR_RHOS4]] A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter.<ref>PMID:21249136</ref>
[https://www.uniprot.org/uniprot/ACUR_CERS4 ACUR_CERS4] A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter.<ref>PMID:21249136</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3bru_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3bru_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cereibacter sphaeroides 2 4.1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rhos4]]
[[Category: Freeman L]]
[[Category: Freeman, L]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A]]
[[Category: Maltseva N]]
[[Category: Structural genomic]]
[[Category: Osipiuk J]]
[[Category: Maltseva, N]]
[[Category: Osipiuk, J]]
[[Category: Apc88928]]
[[Category: Dna-binding]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tetr]]
[[Category: Transcription]]
[[Category: Transcription regulation]]

Latest revision as of 10:53, 9 October 2024

Crystal structure of regulatory protein TetR from Rhodobacter sphaeroidesCrystal structure of regulatory protein TetR from Rhodobacter sphaeroides

Structural highlights

3bru is a 2 chain structure with sequence from Cereibacter sphaeroides 2.4.1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ACUR_CERS4 A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Sullivan MJ, Curson AR, Shearer N, Todd JD, Green RT, Johnston AW. Unusual regulation of a leaderless operon involved in the catabolism of dimethylsulfoniopropionate in Rhodobacter sphaeroides. PLoS One. 2011 Jan 7;6(1):e15972. doi: 10.1371/journal.pone.0015972. PMID:21249136 doi:http://dx.doi.org/10.1371/journal.pone.0015972

3bru, resolution 2.30Å

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OCA
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