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Aldolase 3D structures: Difference between revisions

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Fructose–1,6-bisphosphate aldolase
*Fructose–1,6-bisphosphate aldolase or fructose-bisphosphate aldolase


**[[1xfb]], [[1qo5]], [[2ald]], [[1ald]], [[5ky6]] – hFBPA – human<br />
**[[1xfb]], [[1qo5]], [[2ald]], [[1ald]], [[5ky6]] – hFBPA – human<br />
**[[1xdl]], [[1xdm]] – hFBPA (mutant)<br />
**[[1xdl]], [[1xdm]] – hFBPA (mutant)<br />
**[[8d44]] - hFBPA B – Cryo EM<br />
**[[7u5j]] - bFBPA – bovine - Cryo EM<br />
**[[1zah]], [[1fdj]], [[1ewd]], [[1ewe]], [[1ex5]], [[1ado]], [[5vy5]], [[7ka4]] - rFBPA – rabbit<br />
**[[1zah]], [[1fdj]], [[1ewd]], [[1ewe]], [[1ex5]], [[1ado]], [[5vy5]], [[7ka4]] - rFBPA – rabbit<br />
**[[3dfn]], [[3dfp]], [[3dfq]], [[3dft]], [[2bv4]], [[3b8d]], [[3bv4]], [[5f4x]] – rFBPA (mutant)<br />
**[[3dfn]], [[3dfp]], [[3dfq]], [[3dft]], [[2bv4]], [[3b8d]], [[3bv4]], [[5f4x]] – rFBPA (mutant)<br />
**[[6v20]], [[7k9l]], [[7k9x]], [[7ka2]], [[7ka3]], [[7vdc]] - rFBPA – Cryo EM<br />
**[[6v20]], [[7k9l]], [[7k9x]], [[7ka2]], [[7ka3]], [[7vdc]], [[8ehg]], [[8ew2]], [[8twk]], [[8twl]], [[8twm]] - rFBPA – Cryo EM<br />
**[[1fba]] – FBPA – ''Drosophila melanogaster''<br />
**[[1fba]] – FBPA – ''Drosophila melanogaster''<br />
**[[1ojx]], [[1ok6]] – TptFBPA – ''Thermoproteus tenax''<br />
**[[1ojx]], [[1ok6]] – TptFBPA – ''Thermoproteus tenax''<br />
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**[[1l6w]], [[4s1f]] – EcF6PA 1 <br />
**[[1l6w]], [[4s1f]] – EcF6PA 1 <br />
**[[4rz4]], [[4rxg]], [[4rxf]], [[5zol]] – EcF6PA 1 (mutant)<br />
**[[4rz4]], [[4rxg]], [[4rxf]], [[5zol]] – EcF6PA 1 (mutant)<br />
**[[7qxf]] – EcF6PA 1 (mutant) + ligand<br />


*Deoxyribose-phosphate aldolase
*Deoxyribose-phosphate aldolase
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**[[6msw]] – BhDERA (mutant) – ''Bacillus halodurans''<br />
**[[6msw]] – BhDERA (mutant) – ''Bacillus halodurans''<br />


*Dihydroneopterin aldolase
*7,8-dihydroneopterin aldolase


**[[1sql]] – AtDHNPA + guanine <br />
**[[1sql]] – AtDHNPA + guanine <br />
**[[3r2e]] – YpDHNPA – ''Yersinia pestis''<br />
**[[3r2e]] – YpDHNPA – ''Yersinia pestis''<br />
**[[6ojo]] – YpDHNPA + pterin <br />
**[[6ojo]], [[7su4]], [[7su7]] – YpDHNPA + pterin <br />
**[[7su6]] – YpDHNPA (mutant) + dihydroneopterin<br />
**[[2cg8]] – SpDHNPA – ''Streptpcoccus pneumoniae''<br />
**[[2cg8]] – SpDHNPA – ''Streptpcoccus pneumoniae''<br />
**[[2o90]] – EcDHNPA + neopterin<br />
**[[2o90]] – EcDHNPA + neopterin<br />
**[[2nm2]], [[2nm3]], [[1u68]], [[2dhn]] - SaDHNPA + neopterin<br />
**[[2nm2]], [[2nm3]], [[1u68]], [[2dhn]] - SaDHNPA + neopterin<br />
**[[8su7]] – BaDHNPA <br />
**[[5f3m]] – BaDHNPA + neopterin <br />
**[[5f3m]] – BaDHNPA + neopterin <br />
**[[8sv5]] – BaDHNPA + dihydropterin derivative<br />
**[[1rri]], [[1rrw]], [[1rry]], [[1rs2]], [[1rs4]], [[1rsd]], [[1rsi]], [[1dhn]] - SaDHNPA + inhibitor<br />
**[[1rri]], [[1rrw]], [[1rry]], [[1rs2]], [[1rs4]], [[1rsd]], [[1rsi]], [[1dhn]] - SaDHNPA + inhibitor<br />
**[[1z9w]] – MtDHNPA<br />
**[[1z9w]] – MtDHNPA<br />
**[[3v9o]] - DHNPA + guanine – ''Burkholderia thailandensis''<br />
**[[3v9o]] - DHNPA + guanine – ''Burkholderia thailandensis''<br />
**[[5far]] – BcDHNPA + methylguanine – ''Bacillus cereus''<br />
**[[5far]] – BcDHNPA + methylguanine – ''Bacillus cereus''<br />
**[[8evk]] – HpDHNPA + pterin <br />


*HpcH/HpaI aldolase or 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase or Metal-dependent pyruvate aldolase
*HpcH/HpaI aldolase or 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase or Metal-dependent pyruvate aldolase
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**[[3noj]] – PpCHA-ALD – ''Pseudomonas putida''<br />
**[[3noj]] – PpCHA-ALD – ''Pseudomonas putida''<br />


*Oxovalerate aldolase
*4-hydroxy-2-oxovalerate aldolase


**[[1nvm]] – OVA + acetaldehyde dehydrogenase - ''Pseudomonas''<br />
**[[1nvm]], [[8ix7]] – OVA + acetaldehyde dehydrogenase - ''Pseudomonas''<br />
**[[4jn6]] – MtOVA + acetaldehyde dehydrogenase<br />
**[[4jn6]] – MtOVA + acetaldehyde dehydrogenase<br />
**[[4lrs]], [[4lrt]] – OVA + acetaldehyde dehydrogenase – ''Thermomonospora curvata''<br />
**[[4lrs]], [[4lrt]] – OVA + acetaldehyde dehydrogenase – ''Thermomonospora curvata''<br />
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**[[7ne2]] – SeSFP +SFP/DHAP <br />
**[[7ne2]] – SeSFP +SFP/DHAP <br />
**[[7ag1]] – EcSFP <br />
**[[7ag1]] – EcSFP <br />
**[[8q59]] – YaSFP + sulfofructose phosphate – ''Yersinia aldovae''<br />
**[[8q57]] – YaSFP + sulfate<br />


*Phospho-2-dehydro-3-deoxyheptonate aldolase
*Phospho-2-dehydro-3-deoxyheptonate aldolase
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**[[2vws]] – EcALDII<br />
**[[2vws]] – EcALDII<br />
**[[2vwt]] – EcALDII + pyruvate <br />
**[[2vwt]] – EcALDII + pyruvate <br />
**[[8q5a]] – ALDII + DHAP – ''Hafnia paralvei''<br />


*Fructose–1,6-bisphosphate aldolase
*Fructose–1,6-bisphosphate aldolase
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**[[6btd]] – BtFPA – ''Bacillus thuringiensis''<br />
**[[6btd]] – BtFPA – ''Bacillus thuringiensis''<br />
**[[6btg]] – BtFPA + DHAP <br />
**[[6btg]] – BtFPA + DHAP <br />
**[7x78f]] – FPA – ''Klebsiella pneumoniae''<br />
**[[7x78]] – FPA – ''Klebsiella pneumoniae''<br />
 
*HpcH/HpaI aldolase or 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase or Metal-dependent pyruvate aldolase
 
**[[3qz6]] – HPA – ''Desulfitobacterium hafniense''
**[[2v5j]] – EcHPA
**[[2v5k]] – EcHPA + oxamate
**[[4l7z]] – CaHHALD – ''Chloroflexus aurantiacus''<br />
**[[4l80]] – CaHHALD + oxalate + propionyl-CoA<br />
**[[4mf4]] – BcHHALD - ''Burkholderia cenocepacia'' <br />
**[[6kin]] – RcHHALD – ''Roseiflexus castenholzii''<br />
**[[6kkh]] – RcHHALD + oxalate <br />
**[[7nuj]], [[7o5i]], [[7o5r]] – SwHHALD – ''Sphingomonas wittichii''<br />
**[[7nr1]], [[7o5w]], [[7o9r]], [[7obu]] - SwHHALD (mutant)<br />
**[[6r62]] – SwHHALD + hydroxypyruvate <br />
**[[7o5v]], [[7o87]] – SwHHALD (mutant) + hydroxypyruvate <br />
**[[8adq]] – SwHHALD + hydroxypyruvate + glyceraldehyde<br />
**[[4b5x]] – EcPyrA (mutant)
**[[4b5s]] – EcPyrA + pyruvate + Co + Mg
**[[4b5w]] – EcPyrA (mutant) + pyruvate + Co
**[[4b5t]] – EcPyrA + keto-butyrate + Co + Mg
**[[4b5u]] – EcPyrA + succinic semialdehyde + Co + Mg
**[[4b5v]] – EcPyrA + pyruvate + heptanedioate derivative + Mg
**[[tet8]] – AbHpai + Ca <br />
**[[7etd]] – AbHpai + Ca + Zn<br />
**[[7ete]] – AbHpai + Ca + Mg<br />
**[[7etb]], [[7etf]] – AbHpai + pyruvate + Ca + Mn<br />
**[[7et9]], [[7eta]], [[7etc]], [[7etg]], [[7eth]], [[7eti]] – AbHpai + pyruvate + Ca + Zn<br />


*Sphingosine-1-phosphate Aldolase or Sphingosine-1-phosphate lyase
*Sphingosine-1-phosphate Aldolase or Sphingosine-1-phosphate lyase


**[[4q6r]] – hSPL + inhibitor<br />
**[[8ayf]] – hSPL + PLP derivative<br />
**[[3mc6]] – ySCDPL1 (mutant) <br />
**[[3mc6]] – ySCDPL1 (mutant) <br />
**[[4q6r]] – hSPL + inhibitor<br />


*Rhamnulose-1-phosphate aldolase
*Rhamnulose-1-phosphate aldolase
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**[[6qkb]] – HAspA – ''Paracoccus dentrificuans''<br />
**[[6qkb]] – HAspA – ''Paracoccus dentrificuans''<br />


*Threonine aldolase
*L-Threonine aldolase


**[[8pum]], [[8pus]] – mL-ThrA - mouse<br />
**[[2fm1]], [[1m6s]], [[1jg8]] – TmThrA<br />
**[[2fm1]], [[1m6s]], [[1jg8]] – TmThrA<br />
**[[1lw4]], [[1lw5]] – TmThrA + amino acid<br />
**[[1lw4]], [[1lw5]] – TmThrA + amino acid<br />
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**[[3wgb]] – AjThrA – ''Aeromonas jandaei''<br />
**[[3wgb]] – AjThrA – ''Aeromonas jandaei''<br />
**[[3wgc]] – AjThrA (mutant)<br />
**[[3wgc]] – AjThrA (mutant)<br />
**[[4v15]] – ThrA – ''Achromobacter xylosoxidans''<br />
**[[5vye]] – PpThrA + pyridoxime derivative<br />
**[[5vye]] – PpThrA + pyridoxime derivative<br />
**[[7k34]] – ThrA – ''Pseudomonas fluorescens''<br />
**[[7k34]] – ThrA – ''Pseudomonas fluorescens''<br />
**[[7w0i]] – L-ThrA – Mycobacterium vanbaalenii<br />
**[[7yvr]] – L-ThrA – Neptunomonas marina<br />
*D-threonine aldolase
**[[7yqa]] – CrD-ThrA<br />
**[[4v15]] – D-ThrA – ''Achromobacter xylosoxidans''<br />


*Phenylserine aldolase
*Phenylserine aldolase

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Michal Harel
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