6jfv: Difference between revisions
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<StructureSection load='6jfv' size='340' side='right'caption='[[6jfv]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='6jfv' size='340' side='right'caption='[[6jfv]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6jfv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[6jfv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JFV FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfv OCA], [https://pdbe.org/6jfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jfv RCSB], [https://www.ebi.ac.uk/pdbsum/6jfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfv OCA], [https://pdbe.org/6jfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jfv RCSB], [https://www.ebi.ac.uk/pdbsum/6jfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/K1C14_HUMAN K1C14_HUMAN] Epidermolysis bullosa simplex, Dowling-Meara type;Localized epidermolysis bullosa simplex;Dermatopathia pigmentosa reticularis;Naegeli-Franceschetti-Jadassohn syndrome;Epidermolysis bullosa simplex with mottled pigmentation;Generalized epidermolysis bullosa simplex, non-Dowling-Meara type;KRT14-related epidermolysis bullosa simplex. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/K1C14_HUMAN K1C14_HUMAN] The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.<ref>PMID:11724817</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Coulombe | [[Category: Coulombe PA]] | ||
[[Category: Kim | [[Category: Kim MS]] | ||
[[Category: Leahy | [[Category: Leahy DJ]] | ||
[[Category: Lee | [[Category: Lee CH]] | ||