2k3k: Difference between revisions
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==Solution structure of Drosophila melanogaster SNF RBD1== | ==Solution structure of Drosophila melanogaster SNF RBD1== | ||
<StructureSection load='2k3k' size='340' side='right'caption='[[2k3k | <StructureSection load='2k3k' size='340' side='right'caption='[[2k3k]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br> | <table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cui | [[Category: Cui G]] | ||
[[Category: Hu | [[Category: Hu J]] | ||
[[Category: Jin | [[Category: Jin C]] | ||
[[Category: Liu | [[Category: Liu C]] | ||
[[Category: Xia | [[Category: Xia B]] | ||
Latest revision as of 22:09, 29 May 2024
Solution structure of Drosophila melanogaster SNF RBD1Solution structure of Drosophila melanogaster SNF RBD1
Structural highlights
FunctionSNRPA_DROME Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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