2e5i: Difference between revisions

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==Solution structure of RNA binding domain 2 in Heterogeneous nuclear ribonucleoprotein L-like==
==Solution structure of RNA binding domain 2 in Heterogeneous nuclear ribonucleoprotein L-like==
<StructureSection load='2e5i' size='340' side='right'caption='[[2e5i]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2e5i' size='340' side='right'caption='[[2e5i]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e5i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E5I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e5i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E5I FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hnrpll ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e5i OCA], [https://pdbe.org/2e5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e5i RCSB], [https://www.ebi.ac.uk/pdbsum/2e5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e5i ProSAT], [https://www.topsan.org/Proteins/RSGI/2e5i TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e5i OCA], [https://pdbe.org/2e5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e5i RCSB], [https://www.ebi.ac.uk/pdbsum/2e5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e5i ProSAT], [https://www.topsan.org/Proteins/RSGI/2e5i TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HNRLL_MOUSE HNRLL_MOUSE]] RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.  
[https://www.uniprot.org/uniprot/HNRLL_MOUSE HNRLL_MOUSE] RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Inoue, M]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Muto, Y]]
[[Category: Muto Y]]
[[Category: Structural genomic]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M]]
[[Category: Terada T]]
[[Category: Terada, T]]
[[Category: Tsuda K]]
[[Category: Tsuda, K]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Gene regulation]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rbd]]
[[Category: Rrm domain]]
[[Category: Rsgi]]

Latest revision as of 21:47, 29 May 2024

Solution structure of RNA binding domain 2 in Heterogeneous nuclear ribonucleoprotein L-likeSolution structure of RNA binding domain 2 in Heterogeneous nuclear ribonucleoprotein L-like

Structural highlights

2e5i is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

HNRLL_MOUSE RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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