2orc: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==CRO REPRESSOR INSERTION MUTANT K56-[DGEVK], NMR, 32 STRUCTURES== | ==CRO REPRESSOR INSERTION MUTANT K56-[DGEVK], NMR, 32 STRUCTURES== | ||
<StructureSection load='2orc' size='340' side='right'caption='[[2orc | <StructureSection load='2orc' size='340' side='right'caption='[[2orc]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2orc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2orc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orc OCA], [https://pdbe.org/2orc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orc RCSB], [https://www.ebi.ac.uk/pdbsum/2orc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orc OCA], [https://pdbe.org/2orc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orc RCSB], [https://www.ebi.ac.uk/pdbsum/2orc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 32: | Line 32: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia virus Lambda]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mossing | [[Category: Mossing MC]] | ||