2orc: Difference between revisions

No edit summary
No edit summary
 
Line 1: Line 1:


==CRO REPRESSOR INSERTION MUTANT K56-[DGEVK], NMR, 32 STRUCTURES==
==CRO REPRESSOR INSERTION MUTANT K56-[DGEVK], NMR, 32 STRUCTURES==
<StructureSection load='2orc' size='340' side='right'caption='[[2orc]], [[NMR_Ensembles_of_Models | 32 NMR models]]' scene=''>
<StructureSection load='2orc' size='340' side='right'caption='[[2orc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2orc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2orc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORC FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRO MUTANT K56-[DGEVK] ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orc OCA], [https://pdbe.org/2orc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orc RCSB], [https://www.ebi.ac.uk/pdbsum/2orc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orc OCA], [https://pdbe.org/2orc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orc RCSB], [https://www.ebi.ac.uk/pdbsum/2orc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD]] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.  
[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 32: Line 32:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage lambda]]
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mossing, M C]]
[[Category: Mossing MC]]
[[Category: Gene regulating protein]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA