2bbm: Difference between revisions
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==SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR== | ==SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR== | ||
<StructureSection load='2bbm' size='340' side='right'caption='[[2bbm | <StructureSection load='2bbm' size='340' side='right'caption='[[2bbm]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2bbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. The August 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Calmodulin'' by Shuchismita Dutta and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_8 10.2210/rcsb_pdb/mom_2003_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBM FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbm OCA], [https://pdbe.org/2bbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbm RCSB], [https://www.ebi.ac.uk/pdbsum/2bbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbm OCA], [https://pdbe.org/2bbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbm RCSB], [https://www.ebi.ac.uk/pdbsum/2bbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Calmodulin]] | [[Category: Calmodulin]] | ||
[[Category: | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Bax | [[Category: Bax A]] | ||
[[Category: Clore | [[Category: Clore GM]] | ||
[[Category: Gronenborn | [[Category: Gronenborn AM]] | ||
[[Category: Ikura | [[Category: Ikura M]] | ||