Cefuroxime: Difference between revisions
No edit summary |
No edit summary |
||
| Line 2: | Line 2: | ||
Cefuroxime, sold under the brand name Zinacef among others, is a second-generation [[cephalosporin]]<ref name="a2">Katzung B (2018). Basic & Clinical Pharmacology. McGraw Hill. p. 803.</ref> antibiotic used to treat and prevent a number of bacterial infections.<ref name="a3">British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 518. ISBN 9780857113382.</ref> These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.<ref name="a4">[https://www.drugs.com/monograph/cefuroxime.html "Cefuroxime Sodium Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Retrieved 22 March 2019.</ref> See also [https://en.wikipedia.org/wiki/Cefuroxime Cefuroxime]. | Cefuroxime, sold under the brand name Zinacef among others, is a second-generation [[cephalosporin]]<ref name="a2">Katzung B (2018). Basic & Clinical Pharmacology. McGraw Hill. p. 803.</ref> antibiotic used to treat and prevent a number of bacterial infections.<ref name="a3">British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 518. ISBN 9780857113382.</ref> These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.<ref name="a4">[https://www.drugs.com/monograph/cefuroxime.html "Cefuroxime Sodium Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Retrieved 22 March 2019.</ref> See also [https://en.wikipedia.org/wiki/Cefuroxime Cefuroxime]. | ||
Cefuroxime is active against many bacteria including susceptible strains of Staphylococci and Streptococci, as well as a range of gram negative organisms.<ref name="a9">[https://drug.wellingtonicu.com/appendices/appendix5/ "Appendix 5 – Antibiotic overview".] Wellington ICU Drug Manual. Retrieved 7 April 2023</ref> As with the other cephalosporins, it is susceptible to [[beta-lactamase]], although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike other second-generation cephalosporins, cefuroxime can cross the blood–brain barrier.<ref name="a10"> | Cefuroxime is active against many bacteria including susceptible strains of Staphylococci and Streptococci, as well as a range of gram negative organisms.<ref name="a9">[https://drug.wellingtonicu.com/appendices/appendix5/ "Appendix 5 – Antibiotic overview".] Wellington ICU Drug Manual. Retrieved 7 April 2023</ref> As with the other cephalosporins, it is susceptible to [[beta-lactamase]], although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike other second-generation cephalosporins, cefuroxime can cross the blood–brain barrier.<ref name="a10">Root RK, Waldvogel F, Corey L, Stamm WE (1999). Clinical Infectious Diseases: A Practical Approach. Oxford University Press. p. 259. ISBN 9780195081039</ref> | ||
[[3zg9]]. | [[3zg9]]. | ||